Back to results
US 11,896,593 B2Granted
Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder
AssigneeBio-Pharm Solutions Co., Ltd.
InventorYong Moon Choi
Life of this patent
Estimating the term…
Abstract
The present invention relates to a pharmaceutical composition for treating and/or alleviating a psychiatric disorder comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a pharmaceutical composition for inducing anti-stress, anti-anxiety and/or anti-depressant activities comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient.
Claims13
A method for treating a psychiatric disorder in a subject, comprising:
- selecting a subject having a psychiatric disorder;
- and
- administering to the subject a pharmaceutical composition comprising a sulfamate derivative compound of Chemical Formula I or a pharmaceutically acceptable salt thereof:
- wherein
- R1 and R2 are each independently selected from the group consisting of hydrogen, C1-C5 alkyl, C2-C5 alkenyl and C6-C10 aryl, R1 and R2 together with the carbon atom to which they attach form a C3-C12 cycloalkyl group, or R1 and R2 are bond and they together with the oxygen atom to which they attach form a carbonyl group;
- A is an aryl moiety or a heterocyclic moiety optionally substituted by one or more substituents selected from the group consisting of hydrogen, hydroxyl, C1-C5 alkoxy, C1-C5 alkyl, C2-C5 alkenyl, C6-C10 aryl, C1-C5 alkoxycarbonyl, carboxyl, C2-C5 acyl, C1-C5 alkylthio, cyano, nitro, amine, C1-C5 alkylamine and halogen;
- R3 and R4 are each independently hydrogen or C1-C3 alkyl;
- l and m are each independently an integer of 0˜4;
- and
- the psychiatric disorder is selected from the group consisting of anxiety disorder, mood disorder, somatoform disorder, dissociative disorder, psychotic disorder, personality disorder, sexual disorder, sexual identity disorder, substance-related disorder, eating disorder, sleep disorder, impulse control disorder and adjustment disorder.
7 more elements
Dependencies are inferred from the claim text.