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US 11,896,573 B2Granted
Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative
AssigneeXwpharma Ltd.
InventorsWilliam W. Xiang, Jia-Ning Xiang, Daniel M. Canafax
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Abstract
Pharmaceutical compositions of 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and γ-hydroxybutyric acid following oral administration of the pharmaceutical compositions to healthy subjects are disclosed.
Claims11
A pharmaceutical composition in a form of an aqueous solution comprising:
- from 82 wt % to 92 wt % of 4-((L-valyl)oxy)butanoic acid;
- and
- from 5 wt % to 9 wt % of malic acid, wherein
- wt % is based on the total weight of non-aqueous constituents of the aqueous solution;
- and
- the aqueous solution has a pH from 4.0 to 5.0.
3 more elements
Dependencies are inferred from the claim text.