Compositions comprising amino acids for use in the treatment of mucositides in neoplasia patients undergoing radiation therapy and/or chemotherapy
AssigneeProfessional Dietetics S.R.L.
InventorPaolo Luca Maria Giorgetti
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Abstract
Amino acid composition for use in the treatment of mucositis in patients suffering from head and neck cancer, undergoing radiation therapy and/or chemotherapy, the composition comprising an active agent, the active agent comprising the amino acids: glutamine, leucine, isoleucine, valine, lysine, threonine, histidine, phenylalanine, methionine, tryptophan, tyrosine, and cystine, wherein the glutamine:leucine weight ratio is in the range 4.3 to 5.3.
Claims11
A method of treating mucositis in a patient who is suffering from neoplasia of the cervical-cephalic region and who is undergoing radiation therapy and/or chemoradiotherapy, the method consists of:
- (1) selecting an amino acid composition for use in the treatment of mucositis in the patient who is suffering from neoplasia of the cervical-cephalic region and who is undergoing radiation therapy and/or chemoradiotherapy, the amino acid composition consists of:
- (i) an active agent, said active agent consists of the amino acids glutamine, leucine, isoleucine, valine, lysine, threonine, histidine, phenylalanine, methionine, tryptophan, tyrosine, and cystine, wherein
- (a) the amino acid composition is free of any further different amino acids,
- (b) the glutamine:leucine weight ratio is in the range 4.3 to 5.3, and
- (c) glutamine is present in an amount between 50 and 65% by weight with respect to the total weight of the active agent, and
- (ii) optionally at least one of, none of which have any amino acids:
- carbohydrates, at least one thickening agent, at least one vitamin, pharmaceutically acceptable excipients, and flavouring substances, and
- (2) administering the amino acid composition to the patient to treat mucositis in the patient who is suffering from neoplasia of the cervical-cephalic region and who is undergoing radiation therapy and/or chemoradiotherapy.
Dependencies are inferred from the claim text.