Apparatus and method of using in situ solidifying complex coacervates for vascular occlusion
AssigneeFluidx Medical Technology, LLC
InventorsShawn Patrick Fojtik, Russell Stewart
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Abstract
Described herein are the use of fluid complex coacervates that produce solid adhesives in situ to anchor medical devices such as catheters in a blood vessel. The anchored devices permit the targeted delivery of bioactive agents. The anchored devices can perform as an embolic agent by reducing or preventing blood flow in the vessel. Additionally, the embolic produced from the solid adhesive produced in situ can also include one or more bioactive agents that can be released in a controlled manner.
Claims20
A method for anchoring a catheter in a blood vessel of a subject, the method comprising (a) inserting into a blood vessel of a subject a catheter;
- and (b) injecting into the catheter an injectable composition, wherein the injectable composition comprises water and oppositely charged polyelectrolytes and counterions, wherein the concentration of the counterions in the injectable composition is greater than the concentration of ions in the blood vessel, whereupon introduction of the injectable composition into the blood vessel a solid or gel is produced in situ that seals the catheter to an inner wall of the vessel.
Dependencies are inferred from the claim text.