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US 11,464,848 B2Granted
Respiratory syncytial virus vaccine
AssigneeModernaTX, Inc.
InventorsGiuseppe Ciaramella, Kapil Bahl, Amy Espeseth, Dai Wang, Andrew J. Bett
Life of this patent
Estimating the term…
Abstract
The disclosure describes respiratory syncytial virus (RSV) ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
Claims17
A composition comprising a ribonucleic acid (RNA) polynucleotide having an open reading frame encoding a respiratory syncytial virus (RSV) antigenic polypeptide and a lipid nanoparticle comprising 10-20 mol % neutral lipid, 35-45 mol % cholesterol, 1-5% PEG-modified lipid, and 40-50 mol % ionizable cationic lipid, wherein the ionizable cationic lipid comprises Compound 25:
Dependencies are inferred from the claim text.