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US 11,442,117 B2Granted
Systems, devices, and methods for electroporation induced by magnetic fields
AssigneeSigma Genetics, Inc.
InventorsChristopher James Pihl, Matthew Rein Scholz, David Edwin Kirtley
Life of this patent
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Abstract
A system includes a control device and a magnetic device coupled to the control device. The magnetic device is configured to inductively couple to a treatment target including one or more cells exposed to an agent, and includes one or more magnetic coils. The control device and the magnetic device are collectively configured to generate and apply a transient magnetic field to the treatment target to induce an electric field and porate the one or more cells and to permit the agent to enter the one or more cells.
Claims16
A system, comprising:
- a control device including a set of independent circuits;
- a set of magnetic devices coupled to the control device, the set of magnetic devices configured to magnetically or inductively couple to a treatment target including one or more cells exposed to an agent, each magnetic device of the set of magnetic devices including one or more magnetic coils and being independently addressable by a corresponding circuit of the set of independent circuits;
- and
- a user interface configured to receive an indication of spatial information associated with an application of a set of transient magnetic fields,
- the control device and the set of magnetic devices collectively configured to generate and apply the set of transient magnetic fields based on the indication of spatial information to the treatment target to porate the one or more cells and to permit the agent to enter the one or more cells.
2 more elements
A method, comprising:
- exposing one or more cells in a treatment target to an agent;
- receiving an indication of spatial information associated with an application of a set of transient magnetic field;
- and
- applying the set of transient magnetic fields to the treatment target based on the indication of spatial information to porate the one or more cells and to permit the agent to enter the one or more cells.
1 more element
Dependencies are inferred from the claim text.