Systems and methods for detecting a brain condition
AssigneesRegents of the University of Minnesota, Boston Scientific Scimed, Inc.
InventorsGregory Kermit Peterson, Justin Theodore Nelson, Gregory J. Sherwood
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Abstract
Embodiments herein include a method for detecting a brain condition in a subject. The method can include obtaining a breath sample from the subject and contacting it with a chemical sensor element, where the chemical sensor element includes a plurality of discrete graphene varactors. The method can include sensing and storing capacitance of the discrete graphene varactors to obtain a sample data set and classifying the sample data set into one or more preestablished brain condition classifications. Other embodiments are also included herein.
Claims15
A method for detecting a severe brain injury in a subject, comprising:
- obtaining a breath sample from the subject using a breath sensing device comprising a chemical sensor element, and contacting the breath sample with the chemical sensor element, the chemical sensor element comprising a plurality of discrete graphene varactors;
- sensing and storing capacitance of the discrete graphene varactors with the breath sensing device to obtain a sample data set across a range of bias voltages from −3 V to 3 V;
- classifying the sample data set with the breath sensing device into one or more preestablished brain injury classifications by comparing the sample data set against one or more previously determined patterns using a pattern matching or a pattern recognition algorithm, wherein the one or more previously determined patterns are characteristic of specific brain condition states;
- identifying the subject as having a severe brain injury;
- and
- initiating administration of at least one selected from a diuretic, an anti-seizure drug and a coma-inducing drug to the subject.
A method of treating an ischemic brain injury in a subject, comprising:
- obtaining an exhaled breath sample from the subject using a breath sensing device comprising a chemical sensor element, and contacting the breath sample with the chemical sensor element, the chemical sensor element comprising a plurality of discrete graphene varactors;
- sensing and storing capacitance of the discrete graphene varactors with the breath sensing device to obtain a sample data set across a range of bias voltages from −3 V to 3 V;
- classifying the sample data set with the breath sensing device into one or more preestablished brain injury classifications by comparing the sample data set against one or more previously determined patterns using a pattern matching or pattern recognition algorithm, wherein the one or more previously determined patterns are characteristic of specific brain condition states;
- identifying the subject as having an ischemic brain injury;
- and
- administering a tissue plasminogen activator to the subject.
Dependencies are inferred from the claim text.