Ribosomal ribonucleic acid hybridization for organism identification
AssigneesThe Broad Institute, Inc., The General Hospital Corporation
InventorsRoby Bhattacharyya, Deborah Hung, Jonathan Livny
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AssigneesThe Broad Institute, Inc., The General Hospital Corporation
InventorsRoby Bhattacharyya, Deborah Hung, Jonathan Livny
Estimating the term…
The present disclosure relates to method of distinguishing between two or more species of one or more organisms in a sample, by contacting a biological sample comprising ribosomal ribonucleic acid (rRNA) with a set of antisense probes, wherein the set of probes contains at least one detectable probe that is specific for a target rRNA sequence of each species to be tested, and wherein the individual probes specific for each species comprises less than about 85% sequence identity; and, detecting hybridization between one or more of the probes and the rRNA, thereby distinguishing between two or more species in a sample.
A method of detecting bacterial rRNA sequences in a sample, comprising:
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