Cell transplant device and method of manufacturing the same

A method for cell transplantation, which comprises transplanting, to a subject in need of angiogenesis, a cell transplant device including a cell structure (A) that has a plurality of biocompatible polymer blocks and a plurality of cells of at least one type, and in which at least one of the plurality of biocompatible polymer blocks is disposed in gaps between the plurality of cells;

• and an immunoisolation membrane (B) that encloses the cell structure;
• wherein the immunoisolation membrane is a porous membrane including a polymer;
• wherein, within an inner side of the porous membrane, a layered compact portion in which a pore diameter is minimized is present, and a pore diameter continuously increases in a thickness direction from the compact portion toward at least one surface of the porous membrane;
• wherein the inner part of the layered compact portion is not in contact with the surface of the membrane;
• and
• wherein the compact portion is located between any one surface of the porous membrane and a portion at a distance of two-fifth of the thickness of the porous membrane from the surface.