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US 11,439,841 B2Granted
Methods and devices for treatment of subcutaneous fat
AssigneeLightfective Ltd
InventorYotam Zimmerman
Life of this patent
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Abstract
Disclosed are methods and devices suitable for transdermally killing adipocytes in a subcutaneous fat layer of a human subject.
Claims19
A skin illumination device for treating subcutaneous fat of a subject, comprising:
- a panel that comprises:
- a plurality of LEDs operable to generate light in a near-infrared range to transdermally heat subcutaneous fat of the subject, the LEDs being arranged in a matrix with rows;
- a substrate for positioning proximate to epidermis of the subject, the substrate being transparent to permit light from the LEDs to pass through;
- a frame to which the LEDs and the substrate are mounted, the frame having a plurality of coolant conduits located between the rows of the LEDs, the coolant conduits being configured to transport a cooling-liquid to cool the LEDs and the substrate;
- a generator configured to generate a pulsed electromagnetic field having a field strength of between 10 Gauss and 30 Gauss and a frequency of between 0.1 Hz and 100 Hz;
- and
- wherein each LED is individually activatable and is operable to be activated alone or together with all or a portion of the other LEDs.
4 more elements
A method for cosmetic treatment of skin of a subject, comprising:
- providing a skin illumination device having a panel with a matrix of LEDs configured to generate light in near-infrared range;
- applying the panel of the skin illumination device to epidermis of the subject;
- operating the skin illumination device to generate light in a near-infrared range with wavelengths selected to penetrate through the epidermis and dermis of the subject;
- employing an intensity of the light to penetrate through the epidermis and the dermis to heat adipocytes in a portion of a subcutaneous fat layer of the subject;
- concurrently applying a pulsed electromagnetic field to the volume of tissue that includes the subcutaneous fat layer;
- wherein the pulsed electromagnetic field has a field strength of not less than 10 Gauss and not more than 30 Gauss and has a magnetic pulse frequency of not less than 0.1 Hz and not more than 100 Hz;
- and
- initiating adipocytes apoptosis and destroying adipocytes.
5 more elements
A method for cosmetic treatment of a portion of a human body, comprising:
- employing an incoherent multi-source and multi-wavelength illumination light for, transdermally heating a portion of a subcutaneous fat layer of a subject and wherein illumination at a surface of epidermis has a cross-sectional area with dimensions of 35 cm2 with a power density of 1.6 W/cm2, the heating sufficient to destroy at least one adipocyte in the portion of the subcutaneous fat layer and to initiate apoptosis thereof;
- applying a pulsed electromagnetic field to the volume of tissue that includes the subcutaneous fat layer, the electromagnetic field having a field strength of between 10 Gauss and 30 Gauss and a frequency of between 0.1 Hz and 100 Hz;
- and
- cooling the portion of epidermis sufficiently to prevent burn damage to the epidermis;
- and
- wherein the illumination includes wavelengths in a near-infrared range of 850 nm to 1100 nm.
3 more elements
Dependencies are inferred from the claim text.