Methods for using anti-myostatin antibodies
AssigneeScholar Rock, Inc.
InventorsGregory J. Carven, Michelle Straub, Adriana Donovan, Katherine Jane Turner
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Abstract
Aspects of the present disclosure relate to antibodies that specifically bind proMyostatin and/or latent Myostatin and uses thereof.
Claims12
A method of preventing muscle loss and/or reducing muscle atrophy in a subject, the method comprising administering to a subject in need thereof an effective amount of an antibody that specifically binds pro/latent myostatin, wherein the antibody comprises a heavy chain comprising an amino acid sequence of SEQ ID NO:50 and a light chain comprising an amino acid sequence of SEQ ID NO:51.
A method of treating a subject having, or at risk of developing, spinal muscular atrophy (SMA), the method comprising administering to the subject an effective amount of an antibody that specifically binds pro/latent myostatin, wherein the antibody comprises a heavy chain comprising an amino acid sequence of SEQ ID NO:50 and a light chain comprising an amino acid sequence of SEQ ID NO:51.
Dependencies are inferred from the claim text.