Lymphocyte and monocyte populations in cancer patients and autologous stem cell preparations, and uses thereof
AssigneeMayo Foundation for Medical Education and Research
InventorsLuis F. Porrata, Svetomir N. Markovic
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Abstract
Provided herein are materials and methods for assessing ratios of lymphocyte to monocytes in cancer patients and, based on the ratios, treating the cancer patients with an immunotherapeutic.
Claims5
A method for treating a cancer patient, said method comprising administering a pharmaceutical composition comprising an immunotherapeutic agent to a cancer patient identified as having a biological sample with a natural killer (NK):CD14+HLA-DRDIM ratio less than 0.29, wherein the cancer is non-Hodgkin's lymphoma, and wherein the immunotherapeutic agent is IL-15, IL-21, or a combination thereof.
Dependencies are inferred from the claim text.