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US 11,439,668 B2Granted
Methods to differentiate stem cells into hormone-producing cells
AssigneeJangoBio, LLC
InventorsCraig S. Atwood, Sivan Vadakkadath Meethal
Life of this patent
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Abstract
Methods are described for differentiating stem and post-natal cells into sex hormone-producing cells that can be administered to a patient autologously or allogeneically in order to maintain in balance, or rebalance, their hypothalamic-pituitary-gonadal (HPG) axis.
Claims5
A method of differentiating cells, the method comprising:
- incubating mesenchymal stem cells with a combination of SF-1 and WT1 agonists and inverse agonists to induce the cells to differentiate into gonadal hormone- producing cells.
Dependencies are inferred from the claim text.