Methods and compositions to prevent and treat inflammation and allergic reactions
AssigneeThe Regents of the University of California
InventorsRichard L. Gallo, Tatsuya Dokoshi
Life of this patent
Estimating the term…
Abstract
The disclosure relates to compositions and methods for treating infection, allergic reactions, colitis, IBD, contact dermatitis, psoriasis, atopic dermatitis, graft vs. host disease and disorders and other disease and disorders comprising dendritic cell activation as well as compositions and method to improve allergen sensitization.
Claims16
A composition comprising therapeutically effective amounts of substantially purified oligosaccharide fragments of hyaluronan (OligoHA) and/or therapeutically effective amounts of a substantially purified enzyme that degrades hyaluronan into oligosaccharide fragments, wherein the composition comprises 60% or more by weight of a combination of tri-, tetra- and hexa-saccharide fragments of hyaluronan.
Dependencies are inferred from the claim text.