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US 11,439,652 B2Granted
Ophthalmic aqueous composition
AssigneesSanten Pharmaceutical Co., Ltd., Daiichi Sanyo Company, Limited
InventorsYoko Endo, Kyohei Takahashi, Shinya Umezaki
Life of this patent
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Abstract
An ophthalmic aqueous composition comprises levofloxacin, a salt thereof, or a solvate thereof; dexamethasone, an ester thereof, or a salt thereof; and one or at least two isotonic agents. The ophthalmic aqueous composition is substantially free of sodium chloride. This ophthalmic aqueous composition is excellent in drug stability and drug migration and has a clear appearance.
Claims14
An ophthalmic aqueous composition consisting essentially of:
- levofloxacin, a salt thereof, or a solvate thereof;
- phosphate ester of dexamethasone or a salt thereof as active ingredients;
- one or at least two isotonic agents;
- and benzalkonium chloride as additives;
- water;
- and
- optionally containing at least one of a buffer, a pH adjuster, a nonionic surfactant, or a stabilizer.
4 more elements
Dependencies are inferred from the claim text.