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US 11,439,600 B2Granted
Abuse deterrent oral solid dosage form
AssigneeSun Pharma Advanced Research Company Ltd.
InventorsNitin Dharmadhikari, Yashoraj Zala, Abhishek Jain, Bramhanand Hanamannavar, Umesh Pai
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Abstract
An abuse deterrent oral solid dosage form comprising: an inner portion comprising a drug susceptible to abuse and a pH dependent polymer soluble in acidic medium an outer portion, wherein the portion is devoid of drug susceptible to abuse and comprises an immediate release form of alkalizer and a sustained release form of alkalizer, the sustained release form of alkalizer comprising an alkalizer and a rate controlling excipient.
Claims16
An abuse deterrent oral solid dosage form comprising:
- an inner portion comprising a drug susceptible to abuse, a first immediate release form of one or more alkalizers and a pH dependent polymer soluble in acidic medium, and
- an outer portion, wherein the outer portion is devoid of drug susceptible to abuse and comprises a mixture of:
- a second immediate release form of one or more alkalizers;
- and
- a sustained release form of an alkalizer, the sustained release form comprising an alkalizer and a rate controlling excipient.
2 more elements
Dependencies are inferred from the claim text.