Two-way pressure relief valve for reservoir

A medical fluid reservoir system, comprising:

• a reservoir shell, the reservoir shell defining an interior space inside of the reservoir shell that is configured to contain a medical fluid and an exterior space that is outside of the reservoir shell;
• and
• a differential pressure relief valve that is coupled to the reservoir shell, the differential pressure relief valve comprising:
• a main body adapted to mount to a wall of the reservoir, wherein the main body has a central chamber defining an outer radial seat, wherein the main body has a positive-pressure port at a center axis with an inner radial seat, and wherein the main body has a negative-pressure port comprising an internal passage spanning the outer radial seat;
• a sealing disk having an anchor body retained in the central chamber and a flexible diaphragm biased against the outer radial seat, wherein the anchor body defines an axial passage coupling the central chamber to an ambient pressure of the exterior space;
• and
• a sealing ball biased against the inner radial seat;
• wherein when a pressure in the interior space exceeds the ambient pressure by a positive-pressure threshold, then the sealing ball is lifted off the inner radial seat to exhaust a gas through the positive-pressure port and the axial passage to the exterior space;
• and
• wherein when the pressure in the interior space is below the ambient pressure by a negative-pressure threshold, then the diaphragm is lifted off the outer radial seat to intake a gas from the atmosphere into the interior space through the axial passage, the internal passage, and the negative-pressure port.