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US 11,433,145 B2Granted
Composition for treating pain
AssigneeKolon Life Science, Inc.
InventorsSujeong Kim, Heonsik Choi, Kyoungbaek Choi, Minjung Kim, Hyeonyoul Lee, Minju Kim, Daewook Kim, Min Kim, Jangjoon Park
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Abstract
The present invention relates to: a composition for alleviating or treating pain, the composition comprising glutamate decarboxylase and a gene coding for an anti-inflammatory cytokine; and a method for alleviating or treating pain by using the composition.
Claims10
A method for relieving or treating pain in a subject with pain comprising administering a composition to the subject,
- wherein the composition comprises
- (a) a first vector comprising a gene encoding glutamate decarboxylase (GAD);
- and
- (b) a second vector comprising a gene encoding interleukin-10 (IL-10),
- wherein the gene encoding GAD and the gene encoding IL-10 are operably linked to expression control sequences;
- wherein the administering the composition relieves the pain, wherein the pain is nociceptive pain, inflammatory pain, or pathological pain;
- and
- wherein the composition is directly administered to a central nervous system of the subject.
5 more elements
Dependencies are inferred from the claim text.