Protection from stress, anxiety, neuroinflammation, and cognitive dysfunction
AssigneeThe Regents of the University of Colorado, a body corporate
InventorsChristopher A. Lowry, Matthew G. Frank, Laura Fonken, Steven F. Maier
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Abstract
Methods of treating or preventing stress, anxiety, or postoperative cognitive dysfunction. Also provided are methods of improving resilience in a subject by administering a therapeutically effective amount of isolated Mycobacterium.
Claims14
A method of inhibiting postoperative cognitive dysfunction (POCD) comprising administering a therapeutically effective amount of an isolated Mycobacterium vaccae to a mammalian subject before or after administering a surgical anesthetic to the subject.
A method of treating or ameliorating the incidence of postoperative cognitive dysfunction (POCD) in a mammalian patient comprising administering a therapeutically effective amount of an isolated M. vaccae to the subject.
Dependencies are inferred from the claim text.