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US 11,433,117 B2Granted
Methods for regulating free fatty acid flux using fat specific protein 27 (FSP27) compositions
AssigneeOhio University
InventorsVishwajeet Puri, John Kopchick, Vishva Sharma
Life of this patent
Estimating the term…
Abstract
Methods and FSP27 compositions for treating and/or preventing metabolic disease and conditions associated insulin resistance, obesity, inflammation and dyslipidemia are described.
Claims3
A method for treating a subject suffering from a metabolic disease associated with one or more of increased free fatty acids and lipotoxicity, comprising
- directly administering to adipose fat cells and tissues of the subject in need thereof a recombinant peptide comprising SEQ ID NO:
- 2 in an amount sufficient to decrease lipolysis in the adipose fat cells and tissue without the need for gene delivery mechanisms,
- wherein the metabolic disease is dyslipidemia.
A method for reducing the amount of visceral adipose fat in the subject, comprising
- administering to the subject in need thereof an effective amount of a recombinant peptide comprising SEQ ID NO:
- 2, and
- decreasing lipolysis in the visceral adipose fat cells and tissue.
Dependencies are inferred from the claim text.