A method for treating a human with skin cells damaged by particulate matter, comprising administering a composition comprising a Hibiscus syriacus extract as an active ingredient to the human,
- wherein the damaged skin cells express one or more genes selected from the group consisting of IL-36G (NM_019618), PTGS2 (NM_000963), XDH (NM_000379) and S100A7 (NM_002963) in an increased amount compared to prior to exposure to the particulate matter,
- wherein the particulate matter has a diameter of 2.5 μm or less;
- and
- wherein the administering of the composition decreases expression of one or more genes selected from the group consisting of IL-36G (NM_019618), PTGS2 (NM_000963), XDH (NM_000379) and S100A7 (NM_002963) in the human compared to prior to the administration.