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AssigneeGeo-Poland sp. z o.o.
InventorsWlodzimierz Piotr Dobrzynski, Magdalena Anna Bednarek
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The invention relates to the Proline-Rich Polypeptide complex (PRP) derived from the mammalian colostrum for use in the treatment of the disorders and conditions related to the alterations of the Brain-Derived Neurotrophic Factor level as well as modulation thereof, particularly disorders and conditions wherein therapeutic strategy is based on the increasing of the BDNF concentration in blood. The PRP complex is postulated to be used for nutrition of adults, young children/babies and infants to promote and preserve the proper development and function of both immune and nervous system. PRPs may be used for supplementation of modified milk and infant milk formulae to make it closer to breast milk.
A method of treating disorders and conditions related to a decrease or fluctuations of a Brain-Derived Neurotrophic Factor (BDNF) level, said disorders and conditions comprising mild cognition deficit, depressed mood, memory decline, or concentration and memory difficulties, or pertaining to temporary intensive mental activity and tiredness, wherein BDNF diagnosed in a blood serum is a biomarker of said disorders and conditions, the method comprising administering a Proline-Rich Polypeptide complex to a subject in an amount effective to treat said disorders and conditions, the Proline-Rich Polypeptide complex having a molecular weight of up to 10 kDa comprising 16-22% of proline, derived from the mammalian colostrum.
Dependencies are inferred from the claim text.