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US 11,433,092 B2Granted
Compositions and methods of use for wound healing
AssigneeSynedgen, Inc.
InventorsShenda M. Baker, William P. Wiesmann, Stacy M. Townsend
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Abstract
Described herein are a solution, composition, and kit of poly (acetyl, arginyl) glucosamine (PAAG), methods of making the solution, and method of treating wounds with the solution, the method comprising administering to a subject an effective amount of a solution comprising PAAG, wherein the PAAG when administered topically contacts the wound, thereby treating the wound.
Claims18
A method of treating a dermal wound in a subject, the method comprising topically administering to the wound an aqueous pharmaceutical gel comprising
- hydroxypropyl methylcellulose in an amount of about 0.5% to about 5% by weight per volume of the pharmaceutical gel;
- a compound of formula (I)
- wherein:
- n is an integer between 20 and 6000;
- and
- each R1 is independently selected for each occurrence from hydrogen, acetyl,
- wherein at least 25% of R1 substituents are H, at least 1% of R1 substituents are acetyl, and at least 2% of R1 substituents are
- a preservative;
- and
- sterile water, wherein the compound of formula (I) is present in an amount of 0.5% by weight in the pharmaceutical gel;
- wherein 21 days after administration of the aqueous pharmaceutical gel, the dermal wound has a thicker epidermis compared to an untreated wound, thereby treating the wound in the subject.
8 more elements
Dependencies are inferred from the claim text.