Oxprenolol compositions for treating cancer
AssigneeActimed Therapeutics Limited
InventorsAndrew J. S. Coats, Stefan Anker, Jochen Springer
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Abstract
The present invention relates to compositions of S-enantiomer enriched oxprenolol and their use in treating cancer and treating or preventing, in cancer patients, cachexia, body weight loss, lean body mass loss and adipose tissue loss, and improving quality of life and prolonging survival of cancer patients.
Claims20
A method of treating cachexia in an individual having metastatic cancer, wherein the metastatic cancer has spread to an organ selected from the group consisting of lung, bone, liver, brain and lymph node, comprising administering to the individual an effective amount of a composition comprising oxprenolol or a pharmaceutically acceptable salt thereof, wherein the composition is enantiomerically enriched for S-oxprenolol and comprises an enantiomeric excess of at least about 50% of S-oxprenolol.
A method of delaying the development of body weight loss of an individual having metastatic cancer, wherein the metastatic cancer has spread to an organ selected from the group consisting of lung, bone, liver, brain and lymph node, comprising administering to the individual an effective amount of a composition comprising oxprenolol or a pharmaceutically acceptable salt thereof, wherein the composition is enantiomerically enriched for S-oxprenolol and comprises an enantiomeric excess of at least about 50% of S-oxprenolol.
Dependencies are inferred from the claim text.