Pharmaceutical composition for reducing local fat and uses thereof
AssigneeCaliway Biopharmaceuticals Co., Ltd.
InventorYu-Fang Ling
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Abstract
The present invention provides a pharmaceutical composition for reducing localized fat, comprising drug-containing micelles made of surfactants, and curcumin encapsulated in said drug-containing micelles. This pharmaceutical composition for reducing localized fat can reduce the fat at the administration site, and has the advantages of high stability, high bioavailability for fat tissue, few side effects, and sustained release.
Claims21
A method for reducing the subcutaneous fat at a local site of a subject, comprising administering a pharmaceutical composition to the local site of the subject, wherein, the pharmaceutical composition comprises:
- drug-containing micelles;
- and curcuminoid encapsulated in said drug-containing micelles;
- wherein, the drug-containing micelle is a microstructure formed by a pharmaceutically acceptable non-ionic surfactant, and the hydrophilic-lipophilic balance value (HLB value) of the non-ionic surfactant is greater than 10;
- and wherein the weight ratio of the curcuminoid to the non-ionic surfactant is 1:8 to 1:500;
- wherein the non-ionic surfactant comprises polysorbate 80, polyoxyl 15 hydroxystearate, polyoxyethylene castor oil derivatives, or a combination thereof.
Dependencies are inferred from the claim text.