Liquid sample introduction method and liquid sample introduction device

A liquid sample introduction method using a liquid sample introduction device configured to send a liquid sample and a nebulizing gas to an ionization probe of an ion source in an ion analysis device and to nebulize the liquid sample from a tip of the ionization probe with the help of the nebulizing gas, the liquid sample introduction device including a plurality of liquid sample containers each of which is a closed container and a liquid sample is stored, a liquid supply gas path connected at one end to a middle of a channel for supplying the nebulizing gas to the ionization probe and branched into a plurality of sub-paths each end of which is connected to each of the plurality of liquid sample containers above liquid levels of the liquid sample, a channel switching unit configured to selectively connect one outlet port and one of a plurality of inlet ports, a common sample supply channel one end of which is connected to the ionization probe and another end is connected to the outlet port of the channel switching unit, and a plurality of individual sample supply channels one ends of which are connected to the plurality of liquid sample containers below the liquid levels of the liquid samples and other ends are connected to the plurality of inlet ports of the channel switching unit, the method comprising:

• a process of setting one of the plurality of liquid sample containers to be in an empty state, and switching connection of the channel switching unit such that the outlet port and the inlet port connected to the liquid sample container which is in the empty state are connected to each other through one of the plurality of individual sample supply channels at a time of finishing analysis in the ion analysis device.