Systems and methods for functional imaging

A method comprising:

• obtaining structural imaging information of a patient including anatomical volumetric data;
• obtaining functional imaging information of the patient including functional volumetric data;
• generating a tissue-specific anatomical probability map using the structural imaging information;
• generating a tissue-non-specific anatomical probability map using the structural imaging information;
• generating local combined anatomical probability weights using the tissue-specific anatomical probability map, the tissue-non-specific anatomical probability map, and the functional image data;
• re-distributing the functional image data using the local combined anatomical probability weights to provide re-distributed functional volumetric data;
• and
• generating an image using the re-distributed functional volumetric data.

A tangible and non-transitory computer readable medium comprising one or more computer software modules configured to direct one or more processors to:

• obtain structural imaging information of a patient including anatomical volumetric data;
• obtain a functional imaging information of the patient including functional volumetric data;
• generate a tissue-specific anatomical probability map using the structural imaging information;
• generate a tissue-non-specific anatomical probability map using the structural imaging information;
• generate local combined anatomical probability weights using the tissue-specific anatomical probability map, the tissue-non-specific anatomical probability map, and the functional image data;
• re-distribute the functional image data using the local combined anatomical probability weights to provide re-distributed functional volumetric data;
• and
• generate an image using the re-distributed functional volumetric data.