Methods of particle manipulation and analysis
AssigneesThe Trustees of Princeton University, UT-Battelle, LLC, University of Hawaii
InventorsJesse Ault, Sangwoo Shin, Howard A Stone, Jie Feng, Patrick Warren
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Abstract
Methods described herein, in some embodiments, permit extraction of particle structural and/or surface charge data from gradient induced particle motion in channels. In one aspect, a method of manipulating particle motion comprises introducing a fluid into a channel, the fluid comprising particles, and driving particle accumulation to a preselected location in the channel by setting advective velocity of the fluid to offset diffusiophoretic mobility of the particles at the preselected location.
Claims3
A method of determining particle zeta potential comprising:
- providing at least one dead-end pore containing a solute having a first solute concentration;
- introducing colloidal particles having positive diffusiophoretic mobility and a second solute concentration that is less than the first solute concentration;
- measuring the image intensity in the dead-end pore;
- determining a maximum colloidal density based on the image intensity;
- and
- determining the particle zeta potential based on the maximum colloidal density.
Dependencies are inferred from the claim text.