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AssigneeRegents of the University of Minnesota
InventorsJinbo Hu, Philippe Buhlmann, Andreas Stein, Xue Zhen
Estimating the term…
Solid-contact electrodes include a molecular redox buffer that is covalently attached to one of the components of the electrodes. These electrodes can be incorporated into electrochemical sensor systems. The electrode components are an electron conductor, a membrane and optionally, an interlayer. The electrode includes covalent attachment of the molecular redox buffer to the interlayer, to the electron conductor or the membrane. The interlayer includes nanoporous carbon such as CIM-carbon. The molecular redox buffer includes a well-defined redox pair, e.g., a complex of Co(II)/Co(III). The electrodes are ion-selective electrodes (ISEs) or reference electrodes. Methods include constructing solid contact electrodes and using the electrodes in electrochemical sensor systems to determine the quantity of an analyte in a sample. The electrochemical sensor systems include disposable paper-based devices and/or wearable devices for measuring analytes in a sample.
A solid-contact (SC)-electrode comprising a solid electron conductor, an interlayer, a membrane and a molecular redox buffer, wherein the interlayer comprises nanoporous carbon and is located between the solid electron conductor and the membrane, wherein the nanoporous carbon is modified by a reactive functional group selected from the group consisting of azide (—N3), thiol (—SH), trichlorosilane, and alkoxysilane, wherein the molecular redox buffer comprises a metal ion redox couple, the metal ion redox couple comprising a reduced species and an oxidized species, wherein the reduced species and the oxidized species of the molecular redox buffer are covalently attached to the nanoporous carbon in the interlayer through the reactive functional group.
A method of making an electrochemical sensor system, the method comprising:
A method of measuring an analyte in a sample comprising:
Dependencies are inferred from the claim text.