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US 11,306,389 B2Granted
Ultraviolet activated antimicrobial surfaces
AssigneeMetascape LLC
InventorsTerrence S. Mcgrath, Deidre Sewell, Daniel M. Storey
Life of this patent
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Abstract
The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.
Claims20
An antibacterial coated medical implant device, comprising:
- a metal and metal oxide ion plasma deposited nanoparticulate first layer from a target onto a medical device surface, said first layer consisting of metal and metal oxide nanoparticulates substantially free of macroparticulates formed by the process of:
- (a) using ion plasma to deposit the first layer onto the substrate;
- and
- (b) exposing the metal and metal oxide nanoparticulates to ultraviolet (UV) light irradiation during step (a), thereby activating ground state oxygen in the metal oxide to form a reactive oxygen species to provide an antimicrobially active coating on the medical device.
1 more element
An antibacterial bilayer coated medical implant device, comprising:
- a metal and metal oxide ion plasma deposited nanoparticulate first layer from a target onto a medical device surface, said first layer consisting of metal and metal oxide nanoparticulates substantially free of macroparticulates;
- a metal and metal oxide deposited second layer over the first layer, said second layer consisting of mixed sizes of metal and metal oxide macroparticulates ranging from 100 nm up to about 1 micron;
- formed by the process of:
- (a) using ion plasma to deposit the first layer and the second layer onto the substrate;
- and
- (b) exposing the metal and metal oxide nanoparticulates and the macroparticulates to ultraviolet (UV) light irradiation during step (a), thereby activating ground state oxygen in the metal oxide to a reactive oxygen species to provide an enhanced antimicrobially active coating on the medical device.
3 more elements
An antibacterial bilayer coated medical implant device, comprising:
- a metal and metal oxide ion plasma deposited nanoparticulate first layer from a target onto a medical device surface, said first layer consisting of metal and metal oxide nanoparticulates substantially free of macroparticulates;
- a metal and metal oxide deposited second layer over the first layer, said second layer consisting of mixed sizes of metal and metal oxide macroparticulates ranging from 100 nm up to about 1 micron;
- formed by the process of:
- (a) placing the substrate in a vacuum chamber at about 20 degrees Celsius;
- (b) using ion plasma to deposit the first layer and the second layer onto the substrate;
- and
- (c) exposing the metal and metal oxide nanoparticulates and the macroparticulates to ultraviolet (UV) light irradiation in the vacuum chamber during step (b), thereby activating ground state oxygen in the metal oxide to a reactive oxygen species to provide an enhanced antimicrobially active coating on the medical device.
4 more elements
Dependencies are inferred from the claim text.