Long non-coding RNA in cancer
OwnerChandrasekhar Kanduri, Mohamad Moustafa Mahmoud Ali +4inventors
InventorsChandrasekhar Kanduri, Mohamad Moustafa Mahmoud Ali, Luisa Statello, Vijay Suresh Akhade, Santhilal Subhash, Subazini Thankaswamy Kosalai
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Abstract
There are provided polynucleotides that is able to bind to and inhibit the long non coding RNA transcript SCAT7. These polynucleotides can be used for the treatment of cancer. Expression analysis of SCAT7 can be used for diagnosis of cancer.
Claims8
A method for treatment of a cancer which is resistant to chemotherapy comprising administering to a patient who has the cancer which is resistant to chemotherapy a polynucleotide that is able to bind to and inhibit a long non-coding RNA transcript that comprises or consists of the sequence SEQ ID NO 1 or SEQ ID NO 2 or a sequence that has at least 95% sequence identity to SEQ ID NO 1 or SEQ ID NO 2.
Dependencies are inferred from the claim text.