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US 11,306,143 B2Granted
Combination of TIM-4 antagonist and PD-1 antagonist and methods of use
AssigneeBristol-Myers Squibb Company
InventorsSean E. Doyle, Mark J. Selby, Eric Chadwick
Life of this patent
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Abstract
Provided are methods and compositions for treating cancer using an effective amount of a PD-1 antagonist (e.g., an antibody) in combination with a TIM-4 antagonist (e.g., an antibody).
Claims13
A method of treating cancer in a subject, the method comprising administering to the subject an effective amount of an anti-PD-1 antibody and an anti-TIM-4 antibody, wherein the anti-TIM-4 antibody inhibits efferocytosis of tumor cells.
A composition comprising a PD-1 antibody and a TIM-4 antibody.
Dependencies are inferred from the claim text.