Spirooxindole compounds as GSK3B inhibitors and process for preparation thereof

A Spirooxindole compound of formula I

• wherein
• Z is hydrogen, halogen, hydroxy, alkoxy, cyano, or nitro;
• Ring A is a five, six or seven membered ring optionally containing an additional hetero atom;
• X is either absent or CH2;
• Ring B is a triazole or a cyclic amine optionally internally substituted with one or more hetero atoms and optionally substituted with a single substituent Y;
• Y is hydrogen, halogen, azide, hydroxymethyl, aryloxy, hydroxy, alkoxycarbonyl, amide, amino, alkyl, phenyl, pyridinyl, benzyl, or benzoyl, aminoalkyl, Y is optionally substituted with one or more of substituents Ya, wherein Ya is halogen, hydroxy, alkoxy, alkyl, phenyl, pyridinyl, benzyl, benzoyl, aryloxy, nitro, cyano, alkoxycarbonyl or aldehyde;
• each Ya is optionally substituted with one or more substituents Yb, wherein Yb is halogen, hydroxy, alkoxy, alkyl, phenyl, pyridinyl, benzyl, benzoyl, aryloxy, nitro, cyano, alkoxycarbonyl, or aldehyde;
• and
• each Yb is optionally substituted with one or more substituents Yc, wherein Yc is of alkoxycarbonyl, halogen or alkyl.