Crystalline form of a BACE inhibitor, compositions, and use
AssigneeMerck Sharp & Dohme Corp.
InventorsLaura M. Artino, William Morris, Eric Sirota, Richard J. Varsolona
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Abstract
The present invention provides a novel crystalline form of verubecestat (Crystalline Form II of Verubecestat) and pharmaceutically acceptable compositions thereof, each of which may be useful in treating, preventing, ameliorating, and/or delaying the onset of an Aβ pathology and/or a symptom or symptoms thereof. Non-limiting examples of such Aβ pathologies, including Alzheimer's disease and mild cognitive impairment, are disclosed herein.
Claims21
A crystalline form of verubecestat characterized by a powder x-ray diffraction pattern with at least peaks at diffraction angles degrees 2 theta (+/−0.2°) of 10.94 and 14.98 in a powder x-ray diffraction obtained using Cu K alpha radiation.
Dependencies are inferred from the claim text.