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US 11,306,058 B2Granted
Crystalline form of N-butyldeoxygalactonojirimycin
AssigneeIdorsia Pharmaceuticals Ltd
InventorsVitor Oliveira, Ivan Pogorelic, Jean-Paul Roduit
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Abstract
The invention relates to a crystalline form of [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)-piperidine-3,4,5-triol, processes for the preparation thereof, pharmaceutical compositions containing such a crystalline form, and its use as a medicament, especially as glycolipid biosynthesis inhibitor.
Claims62
A crystalline form of the compound f(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol:
- characterized by the presence of peaks in the X-ray powder diffraction diagram at the following angles of refraction 2θ:
- 5.6°, 17.7°, and 21.5°;
- wherein said X-ray powder diffraction diagram is obtained by using combined Cu Kα1 and Kα2 radiation, without Kα2 stripping;
- and the accuracy of the 2θ values is in the range of 2θ+/−0.2°.
1 more element
Dependencies are inferred from the claim text.