US 11,305,078 B2 · Ventilator

Abstract

This invention provides ventilators that provide superior air-oxygen mixing and gas delivery. The ventilators that supply a gas mixture to the lungs of a subject. The gas mixture comprises a first gas (e.g. oxygen) and a second gas (e.g. ambient air). The ventilators comprise a first gas inlet, a second gas inlet, flow modulator of the first gas, a flow modulator of the second gas, a junction configured to mix the first gas and the second gas, a patient interface configured to deliver the gas mixture to a subject, a pressure sensor, a plurality of flow sensors comprising at least a first flow sensor and a second flow sensor, and at least one controller configured for obtaining data from the pressure sensor and flow sensors and controlling the flow modulators to provide a gas mixture having a target pressure and a target oxygen content.

A ventilator system comprising:

an air inlet connected to a first gas line;
an oxygen inlet connected to a second gas line;
a mixing chamber connected to both the first gas line and the second gas line;
an air pump and an air flow sensor both connected to the first gas line downstream of the air inlet and upstream of the mixing chamber;
an oxygen control valve and an oxygen flow sensor both connected to the second gas line upstream of the mixing chamber and downstream of the oxygen inlet;
a mixed gas pressure sensor and a mixed gas flow sensor both connected to a third gas line downstream of the mixing chamber and upstream of a patient interface;
a mixing chamber pressure sensor connected to the mixing chamber;
a controller operably connected to the air pump and the oxygen control valve, and further configured to receive measurement signals from the air flow sensor, the oxygen flow sensor, the mixed gas flow sensor, the mixed gas pressure sensor and the mixing chamber pressure sensor, and to implement a cascaded feedback loop that commands a flow target of a mixture of oxygen to air to achieve a target pressure, wherein the cascaded feedback loop comprises an outer pressure feedback loop and dual inner feedback loops, comprising an oxygen flow control feedback loop and an air flow control feedback loop, wherein the outer pressure feedback loop comprises the controller;
and wherein the controlled is further configured to:
obtain a target pressure,
obtain a target oxygen content,
obtain a pressure reading from the mixed gas pressure sensor (the pressure feedback),
compare the pressure feedback to the target pressure,
determine a pressure error based on the comparison of the pressure feedback and the target pressure,
based on the pressure error, correct the mixed gas flow command
determine a target air flow command and a target oxygen flow command based on the pressure error,
control the air pump based on the target air flow command, and
control oxygen control valve based on the target oxygen flow command;
and wherein the oxygen flow control feedback loop comprises the controller:
obtain a target oxygen flow,
determine an oxygen flow command based on the target oxygen flow,
command the oxygen control valve with the oxygen flow command
determine actual oxygen flow in the second line by obtaining an oxygen flow reading from the oxygen flow,
compare the actual oxygen flow to the target oxygen flow,
determine an oxygen flow error based on the comparison of the actual oxygen flow feedback and the target oxygen flow,
based on the oxygen flow error, and
correct the oxygen flow command based on the oxygen flow error;
and
and wherein the air flow control feedback loop comprises the controller:
obtain a target air flow,
provide an air flow command based on the target air flow,
command the air pump with the air flow command;
determine actual air flow in the first gas line by obtaining an air flow reading from the air flow sensor;
compare the actual air flow feedback to the target air flow;
determine an air flow error based on the comparison of the actual air flow and the target air flow, and
correct the air flow command based on the air flow error.

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Ventilator

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Ventilator

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Abstract

Claims22