Inhalable dry powder pharmaceutical composition
AssigneeMannKind Corporation
InventorsDonald Costello, Peter Richardson, Robert A. Baughman, Mark T. Marino
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Abstract
A method for treating hyperglycemia and/or diabetes in a subject is provided. In particular, the method is directed for the treatment of patients with type 2 diabetes mellitus who have a fasting blood glucose concentration greater than about 8 mM, wherein the patient is administered a formulation comprising a GLP-1 molecule and a diketopiperazine by pulmonary inhalation with a dry powder inhalation system.
Claims6
An inhalable dry powder pharmaceutical composition comprising microparticles comprising crystalline plates with irregular surfaces of 2,5-diketo-3,6-di(4 fumaryl-aminobutyl)piperazine or a pharmaceutically acceptable salt thereof and an antiviral compound, derivative, or analog thereof wherein the antiviral compound, derivative, or analog thereof is acyclovir or ganclovir.
Dependencies are inferred from the claim text.