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US 11,304,990 B2Granted
Use of known compounds—intracellular infections
AssigneeIsr Immune System Regulation Holding AB (Publ)
InventorsOla Winqvist, Emma Lindh, Robert Wallin, Matt Gregory, Steven Moss
Life of this patent
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Abstract
The present invention provides a method of treating intracellular infections, in particular intracellular bacterial, fungal, and protozoal infections.
Claims20
A method of treating or preventing an intracellular infection in a subject in need thereof, comprising administering to the subject an effective amount of a GnRH or a GnRH analog in combination with a sex hormone;
- wherein the intracellular infection is selected from Mycobacterium tuberculosis, Mycobacteria causing atypical disease, Mycobacterium avium and M. intracellulare (also known as Mycobacterium avium-intracellulare complex, or MAC), M. kansasii, M. marinum, M. fortuitum, M. gordinae, Mycoplasma pneumoniae, M. genitalium, M. hominis, Ureaplasma urealyticum, U. parvum, Chlamydophila pneumoniae, Salmonella typhimurium, Toxoplasma gondii, Plasmodium falciparum, P. vivax, Trypanosoma cruzi, Cryptosporidium, Leishmania, Histoplasma capsulatum, Cryptococcus neoformans, and Encephalitozoon cuniculi.
Dependencies are inferred from the claim text.