Inhibiting tumor cell migration by inhibition of kinesin light chain 1, variant 1 (KLC1C)

A method of inhibiting transendothelial migration of tumor cells in a mammalian subject suffering from or in remission from cancer comprising administering to the mammalian subject an effective amount of an agent comprising a peptide that competes with kinesin light chain 1, variant 1 (KLC1C) for binding to its cargo, wherein the peptide comprises a sequence of SEQ ID NO:

• 3 at least 8 residues in length and a cell-penetrating peptide sequence.