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US 11,304,966 B2Granted
Composition comprising HMOs for preventing or reducing nociception
AssigneeGlycom A/S
InventorsBruce McConnell, Louise Kristine Vigsnæs, Sami Damak, Norbert Sprenger, Francis Foata
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Abstract
The application relates to synthetic compositions and methods for preventing or reducing nociception and/or nociceptive sensitivity in a non-infant human. The human is administered a composition comprising 6′-sialyllactose (6′-SL) and/or lacto-N-tetraose (LNT).
Claims22
A method comprising:
- selecting a non-infant human experiencing nociceptive sensitivity;
- selecting an effective amount of one or more human milk oligosaccharides (“HMOs”) chosen from the group consisting of 6′-sialyllactose (6′-SL), and a mixture of 6′-SL and lacto-N-tetraose (LNT);
- and
- reducing the nociceptive sensitivity by administering the selected effective amount of the chosen HMOs to the non-infant human during a selected administration period.
1 more element
A method comprising:
- selecting a non-infant human experiencing fibromyalgia and associated nociceptive sensitivity;
- selecting an effective amount of one or more human milk oligosaccharides (“HMOs”) chosen from the group consisting of 6′-sialyllactose (6′-SL) and a mixture of 6′-SL and lacto-N-tetraose (LNT);
- and
- reducing the nociceptive sensitivity associated with the fibromyalgia by administering the selected effective amount of the chosen HMOs to the non-infant human during a selected administration period.
1 more element
A method comprising:
- selecting a non-infant human experiencing non-celiac wheat sensitivity and associated nociceptive sensitivity;
- selecting an effective amount of one or more human milk oligosaccharides (“HMOs”) chosen from the group consisting of 6′-sialyllactose (6′-SL) and a mixture of 6′-SL and lacto-N-tetraose (LNT);
- and
- reducing the nociceptive sensitivity associated with the non-celiac wheat sensitivity by administering the selected effective amount of the chosen HMOs to the non-infant human during a selected administration period.
1 more element
Dependencies are inferred from the claim text.