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US 11,304,961 B2Granted
Compositions comprising dexamethasone
AssigneeDexcel Pharma Technologies Ltd.
InventorsCaterina Kreyenborg, Elisabeth Meimberg, Corinna Tissen, Karl-Heinz Bannefeld, Tomer Gold
Life of this patent
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Abstract
A pharmaceutical composition useful for the treatment of multiple myeloma in combination with an anti-cancer drug is provided. The pharmaceutical composition includes high-dose dexamethasone or a pharmaceutically acceptable salt or solvate thereof.
Claims28
A pharmaceutical composition comprising:
- i) about 15 to about 25 wt.-% dexamethasone or a pharmaceutically acceptable salt or solvate thereof;
- ii) about 45 to about 60 wt.-% filler;
- iii) about 10 to about 30 wt.-% binder;
- iv) about 2 to about 10 wt.-% disintegrant;
- and
- v) about 0.01 to about 5 wt.-% lubricant;
- wherein presence of all components add to 100 wt.-%, and wherein the pharmaceutical composition is prepared by wet granulation.
4 more elements
An uncoated tablet comprising:
- i) about 15 to about 25 wt.-% dexamethasone or a pharmaceutically acceptable salt or solvate thereof;
- ii) about 45 to about 60 wt.-% filler;
- iii) about 10 to about 30 wt.-% binder;
- iv) about 2 to about 10 wt.-% disintegrant;
- and
- v) about 0.01 to about 5 wt.-% lubricant;
- wherein presence of all components add to 100 wt.-%, and wherein the uncoated tablet is prepared by wet granulation.
4 more elements
Dependencies are inferred from the claim text.