Bioactive extract, fraction of Cassia occidentalis and formulation thereof for bone regeneration

A formulation for fracture healing and protection against corticosteroid-induced musculo-skeletal diseases, wherein the formulation comprises Cassia occidentalis extract and/or bioactive fraction optionally along with one or more pharmaceutically acceptable excipients, wherein the formulation comprises alcoholic extract and/or bioactive fraction in an amount ranging from 2-10% w/w, oil in an amount ranging from 20-60% w/w, surfactant in an amount ranging from 20-40% w/w, co-surfactant in an amount ranging from 12-28% w/w, solubilizer in an amount ranging from 5-10% w/w, and excipients in an amount ranging from 10-60% w/w.