Solid composition for quick ingestion with facilitated swallowing, in the form of solid, non-agglomerated particles, comprising two different types of particles
AssigneeUnither Pharmaceuticals
InventorJean-Luc Pougnas
Life of this patent
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Abstract
A solid composition with rapid ingestion and facilitated swallowing, in the form of non-agglomerated solid particles, said composition comprising the following two different types of particle: Pa particles, with very low solubility in saliva and comprising at least one active ingredient, and Ps particles, rapidly soluble in saliva, characterised by an apparent density equal to or greater than approximately 0.6 g.cm−3, advantageously equal to or greater than approximately 0.7 g.cm−3, and preferably between 0.7 and 1.5 g.cm−3 inclusive.
Claims18
A solid composition for administration to a human or animal individual comprising:
- Pa particles comprising at least one active ingredient in sufficient quantity to administer a desired dose of active ingredient to said human or animal individual, wherein the Pa particles have very low solubility in saliva, and
- Ps particles comprising at least one polyol with low glycaemic index and at least one natural index and at least one natural organic acid or a salt thereof, the weight ratio of the at least one natural organic acid or salt thereof/the at least one polyol with low glycaemic index being between 0.01 and 1 inclusive, the Ps particles having an apparent density equal to or greater than approximately 0.6 g.cm−3 and being rapidly soluble in saliva;
- wherein said Ps particles are present in said composition in sufficient quantity to enable rapid ingestion and facilitated swallowing of said Pa particles in said human or animal individual;
- and
- wherein the composition is in the form of non-agglomerated solid particles.
Particles comprising at least one polyol with low glyaecmic index and at least natural organic acid or salt thereof, the weight ratio of the at least one natural organic acid or a salt thereof/the at least one polyol with low glycaemic index being between 0.01 and 1 inclusive, the particles having an apparent density equal to or greater than approximately 0.6 g.cm−3 and being rapidly soluble in saliva.
Dependencies are inferred from the claim text.