Mitral valve prosthesis

An anchoring element for a heart valve prosthesis, the anchoring element comprising:

• a D-ring upper support having a saddle-shaped perimeter configured to be positioned adjacent to a native valve structure of a patient, the upper support comprising an anterior portion and a posterior portion;
• a tubular skirt comprising an upper end portion and a lower end portion, the upper end portion being coupled about an entirety of the perimeter of the upper support to provide a fluid seal therebetween, the skirt extending along a central axis of the anchoring element;
• and
• a lower support coupled to the lower end portion of the skirt, the lower support being axially spaced apart from and separate from the upper support, wherein the D-ring upper support has a larger diameter than the lower support, the lower support comprising:
• a wire frame body defined by a wire loop undulating to define a plurality of lobes that extend upwardly along a central longitudinal axis of the lower support in an expanded state and are configured to exert pressure against the native valve structure of the patient;
• and
• at least two engagement members extending radially outward from the wire loop in a direction away from the upper support for engaging the native valve structure from a ventricular side wherein the plurality of lobes extend upwardly relative to the at least two engagement members;
• wherein the upper support, the skirt, and the lower support are radially expandable from a collapsed configuration to an expanded configuration for delivery within the patient.

An anchoring element for a heart valve prosthesis, the anchoring element comprising:

• an upper support, configured to be positioned adjacent to a native valve structure of a patient, comprising an anterior portion and a posterior portion, wherein the posterior portion of the upper support extends within a first plane and the anterior portion of the upper support extends within a second plane, and wherein the first plane extends transversely relative to the second plane;
• a lower support, separate from the upper support, configured to engage the native valve structure from a ventricular side, wherein the upper support has a larger diameter than the lower support and the lower support is defined by a single, continuous loop of wire that (i) undulates to define a plurality of lobes extending upwardly along a central longitudinal axis of the lower support in an expanded state and configured to exert pressure against the native valve structure of the patient and (ii) comprises at least two engagement members that extend in a direction opposite the plurality of lobes along the central longitudinal axis of the lower support, wherein the plurality of lobes extend upwardly relative to the at least two engagement members;
• and
• a flexible connector comprising an upper end portion coupled to the upper support and a lower end portion coupled to the lower support;
• wherein the lower support and the upper support are radially expandable from a collapsed configuration to an expanded configuration for delivery within the patient.

An anchoring element for a heart valve prosthesis, the anchoring element comprising:

• an upper support, configured to be positioned adjacent to a native valve structure of a patient, comprising an anterior portion and a posterior portion;
• a lower support, separate from the upper support, configured to engage the native valve structure from a ventricular side, wherein the upper support has a larger diameter than the lower support and the lower support is defined by a single, continuous loop of wire that (i) undulates to define a plurality of lobes extending upwardly along a central longitudinal axis of the lower support in an expanded state and configured to exert pressure against the native valve structure of the patient and (ii) comprises at least two engagement members that extend in a direction opposite the plurality of lobes along the central longitudinal axis of the lower support, wherein the plurality of lobes extend upwardly relative to the at least two engagement members;
• and
• a flexible connector comprising an upper end portion coupled to the upper support and a lower end portion coupled to the lower support;
• wherein the lower support and the upper support are radially expandable from a collapsed configuration to an expanded configuration for delivery within the patient, and in the expanded configuration, a portion of the upper support extends in a first plane and a remainder of the upper support extends in a second plane.