Methods, systems and devices for treatment of cerebrospinal venous insufficiency and multiple sclerosis

A method for treating a rising venous backpressure due to an intrathoracic pressure that affects venous outflow through a cerebrospinal vein involving a stent device comprising:

• providing at least one self-expanding stent member configured to be placed within a right internal jugular vein;
• configuring the at least one self-expanding stent member within the right internal jugular vein to apply a non-continuous force on the right internal jugular vein, the at least one self-expanding stent member having a first applied force;
• providing the at least one self-expanding stent member with a sensor and configuring the sensor to sense a physiological triggering variable, the physiological triggering variable being a rising venous backpressure due to an intrathoracic pressure that affects venous outflow through a cerebrospinal vein;
• providing the at least one self-expanding stent member with a microprocessor and configuring the microprocessor to automatically actuate the at least one self-expanding stent member to apply a second applied force that is different from the first applied force when the sensor senses the physiological triggering variable;
• providing at least one deformable constraining member connected to the at least one self-expanding stent member;
• wherein the at least one self-expanding stent member being initially deployable in a collapsed configuration and thereafter self-expandable to a first expanded configuration, the at least one deformable constraining member being operative to diametrically constrain the at least one self-expanding stent member so that it does not self expand beyond the first expanded configuration;
• and
• wherein all or part of the at least one deformable constraining member being thereafter deformable to a deformed configuration that allows all or part of the at least one self-expanding stent member to further expand to a second expanded configuration, the second expanded configuration of the at least one self-expanding stent configured to exert a varying force in response to information provided by the sensor to the microprocessor.