Computation of hemodynamic quantities from angiographic data

A method for computing a hemodynamic quantity, the method comprising:

• acquiring angiography data from a patient;
• calculating, by a processor, a first flow in a blood vessel with a stenosis based on the angiography data;
• calculating a plurality of second flows in the blood vessel, wherein calculating the plurality of second flows comprises calculating by motion tracking contrast agents representing in the angiography data, and wherein calculating the plurality of second flows comprises iteratively calculating the plurality of second flows from the first flow;
• computing, by the processor, a baseline value of a hemodynamic quantity from the first flow and the stenosis;
• computing, by the processor, values for the hemodynamic quantity from the plurality of second flows;
• determining a sensitivity of the values of the hemodynamic quantity to a difference between the first flow and the plurality of second flows relative to the baseline value of the hemodynamic quantity;
• and
• reporting the sensitivity.

A method for computing a hemodynamic quantity, the method comprising:

• acquiring angiography data from a patient;
• iteratively calculating, by a processor, a first flow in a blood vessel with a stenosis;
• calculating a plurality of second flows in the blood vessel, wherein calculating the plurality of second flows comprises calculating by motion tracking contrast agents representing in the angiography data, and wherein calculating the plurality of second flows comprises iteratively calculating the plurality of second flows from the first flow;
• computing, by the processor, a baseline fractional flow reserve value from the first flow and the stenosis;
• computing, by the processor, fractional flow reserve values from the plurality of second flows;
• determining a sensitivity of the fractional flow reserve values to a difference between the first flow and the plurality of second flows relative to the baseline fractional reserve value;
• and
• reporting the sensitivity.