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US 11,304,637 B2Granted
Enclosed desorption electrospray ionization probes and method of use thereof
AssigneePurdue Research Foundation
InventorsRobert Graham Cooks, Zheng Ouyang, Chien-hsun Chen, Ziqing Lin, Livia Schiavinato Eberlin
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Abstract
The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
Claims10
An ionization device, the device comprising:
- an elongate tube that is at least one meter in length and comprises a proximal end configured to mate with an inlet of a mass spectrometer and open distal end, wherein the elongate tube further comprises an opening in a sidewall located at a distal portion of the elongate tube;
- and
- a desorption electrospray ionization (DESI) source comprising a discharge tube;
- wherein the device is configured such that a portion of the discharge tube is inserted through the sidewall of the elongate tube and terminates prior to the open distal end.
1 more element
Dependencies are inferred from the claim text.