System and method for providing glucose control therapy

A method for providing a glucose control therapy using a lead with multiple electrodes operably positioned proximate to nerves that innervate and are proximate to an organ involved with glucose control, the method comprising:

• selecting one or more modulation electrodes from the multiple electrodes for use to deliver modulation energy and selecting one or more sense electrodes from the multiple electrodes for use to sense neural activity in the nerves;
• delivering modulation energy using the selected one or more modulation electrodes;
• sensing neural activity in the nerves using the selected one or more sense electrodes, and
• determining if the delivered modulation energy captures the nerves based on the sensed neural activity,
• wherein the lead includes at least one distal patch configured to wrap at least partially around tissue including the nerves, the multiple electrodes being on the at least one distal patch, and the lead is configured to be intravascularly fed into position proximate to the nerves,
• wherein delivering modulation energy includes using multiple independent current sources to independently deliver current to two or more of the modulation electrodes, and
• wherein each of the multiple independent current sources is configured to source or sink current, each of the multiple independent current sources including a PDAC configured for use to source current and an NDAC configured for use to sink current.