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US 11,304,604 B2Granted
Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification
AssigneeSpectral Md, Inc.
InventorsJohn Michael DiMaio, Wensheng Fan, Jeffrey E. Thatcher, Weizhi Li, Weirong Mo
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Abstract
Certain aspects relate to apparatuses and techniques for non-invasive optical imaging that acquires a plurality of images corresponding to both different times and different frequencies. Additionally, alternatives described herein are used with a variety of tissue classification applications, including assessing the presence and severity of tissue conditions, such as burns and other wounds.
Claims24
A method of assessing burn severity comprising:
- positioning a subject approximate to a light source and an image acquisition device;
- illuminating a tissue region of the subject using the light source;
- acquiring a plurality of images of the tissue region using the image acquisition device, a first subset of the plurality of images captured at different times and a second subset of the plurality of images captured at different frequency bands;
- classifying a burn status of areas of the tissue region based at least in part on photoplethysmography (PPG) data derived from the first subset of the plurality of images acquired with the image acquisition device and on multispectral data derived from the second subset of the plurality of images;
- generating a classified image based at least in part on the plurality of images and the burn status of the areas of the tissue region;
- and
- segmenting individual pixels of the classified image among a plurality of tissue categories based at least in part on the burn status of the areas of the tissue region corresponding to the individual pixels.
4 more elements
An apparatus for assessing burn severity of a subject comprising:
- one or more light sources configured to illuminate a tissue region;
- one or more image acquisition devices configured to receive light reflected from the tissue region;
- and
- a processor configured to:
- control the one or more light sources and the one or more image acquisition devices to acquire a plurality of images the tissue region, a first subset of the plurality of images captured at different times and a second subset of the plurality of images captured at different frequency bands;
- classify a burn status of areas of the tissue region based on photoplethysmography (PPG) data derived from the first subset of the plurality of images and on multispectral data derived from the second subset of the plurality of images;
- generate a classified image based at least in part on the plurality of images and the burn status of the areas of the tissue region;
- and
- segment individual pixels of the classified image among a plurality of tissue categories based at least in part on the burn status of the areas of the tissue region corresponding to the individual pixels.
6 more elements
Dependencies are inferred from the claim text.