Apparatus, device and method for capsule microscopy

An apparatus for obtaining data for at least one portion within at least one luminal or hollow sample, comprising:

• an optical first arrangement configured to transceive at least one electromagnetic radiation to and from the at least one portion
• wherein the at least one electromagnetic radiation comprises electromagnetic radiation having a plurality of different wavelengths,
• a diffractive optical element comprising a diffraction grating configured to rotate about an axis that is substantially parallel to a central axis of a housing,
• wherein the diffraction grating is configured to disperse the plurality of different wavelengths along different spatial locations of the at least one portion;
• a second arrangement which is configured to forward at least one return radiation from the at least one luminal or hollow sample to an optical microscopy system, wherein at least one portion of an outer periphery of the apparatus has a shape of a pill;
• and
• a third arrangement which includes at least one of (i) a battery arrangement which provides energy to the optical microscopy system, (ii) a radio frequency transmitter arrangement, (ii) a light source arrangement, or (iv) a data storage arrangement;
• an optical fiber drive shaft coupled to a rotational mechanical arrangement,
• wherein the optical fiber drive shaft is coupled to the wavelength dispersive second arrangement such that rotation of the optical fiber drive shaft causes the wavelength dispersive second arrangement to rotate about an axis that is substantially parallel to a central axis of the housing.

An apparatus for obtaining data for at least one portion within at least one luminal or hollow sample, comprising:

• a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the at least one portion;
• a wavelength dispersive second arrangement comprising a diffraction grating which is configured to disperse the at least one electromagnetic radiation and configured to rotate about an axis that is substantially parallel to a central axis of a housing,
• wherein the at least one electromagnetic radiation comprises electromagnetic radiation having a plurality of different wavelengths,
• wherein the diffraction grating is configured to disperse the plurality of different wavelengths along different spatial locations of the at least one portion:
• wherein the housing includes a rigid capsule enclosing the first and second arrangements;
• a tether arrangement connected to a proximal end of the housing and containing an optical fiber drive shaft coupled to a rotational mechanical arrangement,
• wherein the optical fiber drive shaft is coupled to the wavelength dispersive second arrangement such that rotation of the optical fiber drive shaft causes the wavelength dispersive second arrangement to rotate about an axis that is substantially parallel to a central axis of the housing.

An apparatus, comprising:

• a housing comprising a rigid capsule;
• a diffractive optical element comprising a diffraction grating rotatably coupled to the housing and configured to rotate about an axis that is substantially parallel to a central axis of the housing;
• a first transmissive optical element that is mechanically coupled to the housing and optically coupled to the diffractive optical element,
• the first transmissive optical element having a proximal end and a distal end, and
• the first transmissive optical element being configured to:
• receive light at the proximal end,
• emit the received light from the distal end toward the diffractive optical element,
• wherein the diffractive optical element is rotated by a motor while the light is emitted from the distal end of the first transmissive optical element towards the diffractive optical element,
• wherein the light emitted from the distal end of the first transmissive optical element comprises a plurality of different wavelengths of light, and
• wherein the diffraction grating is configured to disperse the plurality of different wavelengths toward different portions of a sample, receive reflected light that has been reflected by the sample at the distal end, and
• emit the reflected light toward a second transmissive optical element that is configured to be optically coupled to a detector.